Patients should be informed of the need for immediate medical attention in case of an erection lasting 4 hours or more. Late treatment of priapism ingoes to damage to the tissues of the penis, resulting in a long-term loss of potency. Cialis should be used with caution in patients with a predisposition to priapism (for example, with sickle cell anemia, multiple myeloma or leukemia) or in patients with anatomical deformity of the penis (for example, with angular curvature, cavernous fibrosis or Peyronie's disease).
Caution should be exercised when prescribing Cialis to patients taking potent inhibitors of CYP3A4 (ritonavir, saquinavir, ketoconazole, itraconazole and erythromycin), since an increase in the effect of Cialis (AUC) was observed while taking these drugs.
The safety and effectiveness of the combination of Cialis with other PDE5 inhibitors and methods of treating erectile dysfunction have not been studied. Patients should be informed about the inadmissibility of taking Cialis in such combinations.
Impotence (also known as erectile dysfunction) is a condition characterized by a disorder of sexual function, as a result of which a man's penis does not reach the proper level of enlargement, straightening and hardening necessary for intercourse.
Also, in this condition, the patient cannot maintain an erection for the period of time that is necessary for the duration of a full-fledged sexual intercourse. Impotence is one of the male sexual dysfunctions. According to the studies of American specialists, a similar disease on a global scale is characteristic of about 150 million men who are already 40 years old.
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The designation "impotence" came into use from the Latin term impotentia coeundi, which describes the inability of a man suffering from this disorder to insert the penis during penetrative intercourse and complete intercourse due to insufficient tension of the penis. It is important to consider that such an erectile dysfunction does not directly affect a man's ability to ejaculate.